PubMed · The Journal of Pathology· Yanli Qian·· 2026-09-09
肿瘤学：Heterozygous germline deletion in Hif3a exacerbates esophageal squamous cell carcinoma development.
Heterozygous germline deletion in Hif3a exacerbates esophageal squamous cell carcinoma development.
AI 导读
原文摘录：Germline variations contribute to esophageal squamous cell carcinoma (ESCC) susceptibility. We identified a germline deletion (exons 7-8) in HIF3A in an ESCC family and investigated its functional impact using CRISPR/Cas9-engineered cells and Hif3a-eKO1 m
来源：PubMed · The Journal of Pathology · pubmed.ncbi.nlm.nih.gov