PubMed · Cancer Research· Alicia Bjornberg·· 3 天前
肿瘤学:Selection for Targeted Therapy Resistance Indirectly Selects for Cancer Cells with Enhanced Phenotypic Plasticity and Evolvability to Orthogonal Stressors.
Selection for Targeted Therapy Resistance Indirectly Selects for Cancer Cells with Enhanced Phenotypic Plasticity and Evolvability to Orthogonal Stressors.
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原文摘录:Resistance to targeted therapies is frequently associated with stem-like features and partial epithelial-to-mesenchymal transition (EMT). … Constraining plasticity could delay resistance and extend response durability
来源:PubMed · Cancer Research · pubmed.ncbi.nlm.nih.gov