急诊与重症医学：Understanding Nrf2 Function in Manganese Neurotoxicity.

原文摘录：The objective of the present review was to summarize and discuss recent findings on the effects of Mn exposure on Nrf2 signaling in the brain and its relationship with other molecular mechanisms of Mn neurotoxicity. … Although the existing data were derived from laboratory studies and environmentally irrelevant doses, it is assumed that Nrf2 signaling may represent a potential therapeutic strategy for preventing Mn neurotoxicity