原文摘录：Elaprase RSS Authorised This medicine is authorised for use in the European Union idursulfase Medicine Human Authorised Application under evaluation CHMP opinion European Commission decision Overview This is a summary of the European public assessment rep … This page was last updated on 06/11/2026
原文摘录：Email Bluesky Facebook LinkedIn Reddit Whatsapp X View saved research The bacterium Vibrio cholerae causes disease in humans, but is also good at securing itself to surfaces in the form of a biofilm.
原文摘录：OBJECTIVES: To develop and validate a shorter Family Satisfaction in the ICU (FS-ICU) questionnaire that reduces survey length while preserving content and psychometric performance for quality improvement and benchmarking.
研究人员针对急性脑损伤（ABI）重症患者机械通气撤离试验结局异质性问题，按COS-STAD/COS-STAD标准开展4轮国际Delphi研究，来自31个国家的多学科小组参与评分。
基于 TRACK-TBI 数据集的回顾性队列研究纳入229例≥17岁、行有创颅内压（ICP）监测且入院未行去骨瓣减压术的颅脑创伤患者，分析住院第1天血 GFAP 与 UCH-L1 浓度与 ICP 及治疗强度水平（TIL）的关系。
FDA CDRH发布早期预警，通报潜在高风险器械问题：Compact Medical对部分批次ButterflyBVM一次性球囊面罩（BVM）复苏器发出紧急医疗器械召回通知，建议移除000109–000117批次，000081–000108批次须每次使用前完成使用前测试。
关注理由：FDA CDRH以Early Alert标记该潜在高风险器械问题，区分需移除批次与仅需使用前测试的批次，可据此跟踪急救通气器械的受影响范围与后续监管更新。
该研究对TTM与TTM2两项随机试验共2789例院外心脏骤停成人患者进行二次分析，采用因果森林与BART等效应导向机器学习方法，评估33°C低温与常温（36.0–37.7°C）对六个月全因死亡率和不良功能结局（mRS 4–6）的影响是否因缺血负荷相关因素及入院时神经学表现而异。
美国一家I级创伤中心2021–2023年回顾性分析151例≥15岁、AAST-OIS III级及以上穿透性肾损伤患者，比较手术（OR）与非手术（保守CM、介入放射IR）管理，主要结局为死亡率，次要结局为肾保留率和初始管理策略成功率（SIMS）。
原文摘录：The origin of the solar corona's million Kelvin temperatures remains a central unsolved problem. While the nanoflare hypothesis is widely accepted and describes magnetic reconnection events at coronal current sheets that are slowly formed by complex drive
原文摘录：The objective of the present review was to summarize and discuss recent findings on the effects of Mn exposure on Nrf2 signaling in the brain and its relationship with other molecular mechanisms of Mn neurotoxicity. … Although the existing data were derived from laboratory studies and environmentally irrelevant doses, it is assumed that Nrf2 signaling may represent a potential therapeutic strategy for preventing Mn neurotoxicity
原文摘录：Exposure to traumatic events induces persistent alterations in defensive behavior that extend beyond associative fear memories, including heightened responses to novel stimuli (stress sensitivity) and sustained defensive states in neutral contexts (stress … This work highlights the importance of distinguishing between associative and non-associative components of fear and suggests that psychedelic-induced plasticity may amplify latent trauma-related states under certain conditions
研究构建了机器学习引导、经月桂酸负载实现静电-疏水协同的分级粒径壳聚糖止血颗粒（CSHP），通过物理封堵联合静电与疏水作用形成致密凝血网络，不依赖全身凝血激活即可抵御动脉血流。