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#外科与麻醉
今天11月8日周日1 条
11月6日周五
  1. PubMed · Anesthesiology

    外科与麻醉：Individualized mean arterial pressure during cardiac surgery The OPTIPAM Randomized Clinical Trial.

    原文摘录：BACKGROUND: Whether targeting an individualized mean arterial pressure (MAP) during cardiac surgery improves outcomes remains uncertain. The balance between improved perfusion and vasopressor-driven blood pressure augmentation is unclear. … Future studies should further investigate this safety signal when evaluating individualized blood pressure targets

  4. PubMed · Urology

    可膨胀阴茎假体手术感染预防标准化围手术期方案的初步单外科医生回顾性经验

    一项回顾性分析2017年1月至2025年12月两家医院单外科医生487例可膨胀阴茎假体（IPP）手术（406例初次植入、58例取出重置、23例部件翻修）的前瞻性维护数据库，采用标准化多模式围手术期感染预防方案，包括MRSA去定植、氯己定洗浴、改良无接触技术、抗生素冲洗和23小时住院观察。

  7. PubMed · Journal of Thoracic and Cardiovascular Surgery

    主动脉瓣感染性心内膜炎主动脉根部脓肿单中心回顾研究：脓肿与不良预后相关，补片修复较扩大手术结局更佳

    一项2019–2024年单中心回顾性研究纳入158例手术治疗的主动脉瓣感染性心内膜炎患者（57%合并主动脉根部脓肿），中位随访1.22年。根部脓肿与MACCE（校正HR 3.15, 95%CI 1.51–6.59, p=0.002）及心衰再住院（SHR 4.54, 1.55–13.30, p=0.006）增加相关。

  8. PubMed · European Urology

    多中心回顾系列报告下腹前入路单孔机器人腹膜后肾输尿管切除术（LAA-SP RNU）治疗上尿路尿路上皮癌的手术技术、围手术期与早期肿瘤学结果

    五家转诊中心对47例上尿路尿路上皮癌患者行下腹前入路单孔机器人肾输尿管切除术（LAA-SP RNU）的回顾性系列（2024年5月至2025年7月）显示，经单个4 cm腹膜外切口完成切除、膀胱袖状切除及选择性淋巴结清扫。

11月5日周四
  1. PubMed · The Annals of Thoracic Surgery

    外科与麻醉：The Society of Thoracic Surgeons 2026 Long-term Risk Models for Lung Cancer Resection.

    原文摘录：BACKGROUND: The Society of Thoracic Surgeons (STS) has designed and validated risk models to predict long-term survival in patients undergoing lung cancer resection.

    关注理由：这条外科与麻醉内容涉及相关临床或研究问题，建议查看原文中的方法与适用范围。

  2. PubMed · World Journal of Surgery

    胃电刺激预防腹部大手术后肠麻痹（STIMULATE）：单中心随机盲法可行性研究

    丹麦奥胡斯大学医院开展单中心随机盲法可行性研究，评估腹膜细胞减灭术联合腹腔热灌注化疗患者术中胃部直接电刺激预防术后肠麻痹（POI）的安全性与可行性。20例随机分组，19例纳入分析，干预组完成率8/10、对照组9/10，治疗耐受良好，最常见不良事件为腹肌痉挛；结果支持开展进一步临床研究。试验注册号NCT05752071。

  3. PubMed · The Annals of Thoracic Surgery

    外科与麻醉：Pharmacological Prevention of Cardiac Surgery-Associated Acute Kidney Injury: Why Trials Failed and a Reimagined Endpoint Framework.

    原文摘录：BACKGROUND: Cardiac surgery-associated acute kidney injury affects approximately one in four adults and is independently associated with perioperative mortality and progression to chronic kidney disease. … Platform designs with biomarker-enriched enrollment could convert the next generation of trials into interpretable tests of kidney protection

    关注理由：这条外科与麻醉内容涉及随机对照研究，值得重点看研究分组、主要终点和实际结果。

  4. PubMed · Biochemical Pharmacology

    外科与麻醉：Acute nociceptive stimulation induces long-lasting constitutive activity of spinal μ-opioid receptors that masks pain sensitization.

    原文摘录：Acute nociceptive stimuli evoke transient pain sensitization that normally resolves after the stimulus has ceased. However, whether this apparent recovery reflects restoration of the nociceptive system to its basal state or active suppression of persisten … Our findings reveal a previously unrecognized homeostatic mechanism underlying pain resolution after acute nociceptive stimulation, and the C-fiber-mediated mechanisms for inducing MOR constitutive activity may provide a clue to develop a therapeutic strategy for sustained analgesia

  5. PubMed · Anesthesiology

    外科与麻醉：Frequency of Adherence to Obstetric Anesthesia Best Practices for Cesarean Delivery: A Multicenter Retrospective Cohort Analysis.

    原文摘录：BACKGROUND: Increasingly, protocols have been developed to optimize obstetric anesthesia care. However, there is a paucity of data on adherence to these guidelines.

    关注理由：这篇外科与麻醉队列研究资料适合了解长期变化，研究对象、随访方式和结局指标建议一起查看。

  6. PubMed · Transplantation

    动物与体外研究提示Piezo1介导的钙信号参与肺移植缺血再灌注损伤中的上皮损伤

    一项结合公共转录组数据、大鼠肺移植与体外氧糖剥夺/复氧模型的研究提示，机械敏感离子通道Piezo1在肺缺血/再灌注损伤（IRI）后上调，伴随肺上皮细胞凋亡、钙超载和线粒体膜电位去极化。Piezo1沉默或抑制可减轻钙积累、减少凋亡信号并改善细胞活力，而Yoda1激活可部分恢复损伤表型。结果提示Piezo1可能是肺移植IRI上皮损伤的潜在调控靶点，但仍属临床前证据。

11月4日周三
  1. PubMed · Diseases of the Colon & Rectum

    基于机器学习的直肠癌手术后严重并发症风险预测模型研究

    韩国某三级转诊中心对2011–2025年间3,503例根治性直肠癌切除吻合患者（3,402例回顾性建模、101例前瞻性验证）开发并时间性内部验证了预测术后30天内Clavien-Dindo ≥3级严重并发症的机器学习模型，回顾性队列严重并发症发生率9.8%、前瞻性队列13.9%。

11月3日周二
11月2日周一
11月1日周日
  1. PubMed · The American Journal of Surgery

    I级创伤中心回顾性研究：III级及以上穿透性肾损伤的非手术与手术治疗结局分析

    美国一家I级创伤中心2021–2023年回顾性分析151例≥15岁、AAST-OIS III级及以上穿透性肾损伤患者，比较手术（OR）与非手术（保守CM、介入放射IR）管理，主要结局为死亡率，次要结局为肾保留率和初始管理策略成功率（SIMS）。

10月30日周五
  1. PubMed · Optics Express

    外科与麻醉：Monolithic carrier-beam steering with milliradian precision and single-voltage control.

    原文摘录：We describe what we believe to be a new class of monolithic beam steering systems. The device operates in the conventional 1550 nm communication band and can continuously steer over a 65.2° range with milliradian precision. … 5 × 10 -5 , and full-wave confirmation of the voltage transfer function at multiple bias points

10月28日周三
  1. PubMed · Chemical Reviews

    外科与麻醉：Mapping Local Environments in Single-Atom Catalysts.

    原文摘录：Single-atom catalysts (SACs) offer exceptional structural resolution for investigating how local environments govern catalytic behavior and, ultimately, for controlling these effects through catalyst design. … By integrating aspects that are often considered separately and highlighting those that remain insufficiently addressed, we provide a roadmap toward the predictive, environment-driven design of SACs and a deeper understanding of catalytic phenomena

10月27日周二
  1. medRxiv · 独立预印本

    外科与麻醉：Educational expectations and needs of individuals scheduled for breast surgery within the Primary Nursing Model: a qualitative study

    原文摘录：BackgroundA diagnosis of breast cancer may represent a potentially destabilizing event, with significant physical, psychological, and social implications. … The transcripts will be analyzed using thematic analysis according to Braun and Clarke, with a ph

    关注理由：这条外科与麻醉内容涉及相关临床或研究问题，建议查看原文中的方法与适用范围。

10月13日周二
  1. PubMed · Analytica Chimica Acta

    外科与麻醉：Oxygen vacancies promote electron transfer in PRT@MnO2-x with boosting oxidase-mimicking activity for dual-mode detection of β-galactosidase.

    原文摘录：Vacancy engineering has been widely applied to modulate the enzyme-like activity of nanomaterials by adjusting their surface/electronic structures and creating additional active sites. … The dual-mode signal sensor is expected to provide more accurate and robust detection of β-Gal than the single-mode probe, and has a wider application prospect

10月7日周三
10月1日周四
  1. Europe PMC · 撤稿与关系监测

    外科与麻醉：Withdrawn as duplicate: Pulmonary Blood Volumes on CT Predict Residual Pulmonary Hypertension Post-Pulmonary Endarterectomy.

    原文摘录：Pulmonary blood volumes (PBV), currently not assessed by computed tomography pulmonary angiography (CTPA), could provide additional information to routine investigations performed for chronic thromboembolic pulmonary hypertension (CTEPH). … Utilizing CTPA-derived PBV post-PEA to identify patients without residual PH can potentially reduce the need for routine postoperative right heart catheterization

9月16日周三
  1. PubMed · Spine

    外科与麻醉：Perioperative Aspirin Continuation is Not Associated With Increased Surgical Morbidity Following Minimally Invasive Anterior-to-Psoas Lumbar Fusion: A Propensity-Matched Analysis.

    原文摘录：STUDY DESIGN: Retrospective cohort study with propensity score matching. OBJECTIVE: To evaluate the impact of perioperative aspirin continuation on surgical and postoperative outcomes following minimally invasive anterior-to-psoas (MIS-ATP) lumbar fusion. … CONCLUSION

    关注理由：这篇外科与麻醉队列研究资料适合了解长期变化，研究对象、随访方式和结局指标建议一起查看。

9月14日周一
  1. PubMed · Spine

    外科与麻醉：Comparison of the Sagittal Age-Adjusted Score and the T4-L1PA Mismatch in Discriminating Proximal Junctional Kyphosis and Failure in Adult Spinal Deformity Surgery.

    原文摘录：STUDY DESIGN: Retrospective single-center study. OBJECTIVE: To compare the discriminative ability of the sagittal age-adjusted score (SAAS) and the T4-L1PA mismatch for proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) after adult s … Correcting the lumbar

8月19日周三
8月15日周六