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PubMed · Journal of Molecular Biology· Soumya Sarathi Ganguly·· 2026-10-07

感染病学:Structural Basis of Substrate Accommodation and Thiourea-mediated Inhibition of the Mycobacterium tuberculosis Dehydratase HadAB.

Structural Basis of Substrate Accommodation and Thiourea-mediated Inhibition of the Mycobacterium tuberculosis Dehydratase HadAB.

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原文摘录:Mycobacterium tuberculosis relies on the fatty acid synthase II (FAS II) pathway for the biosynthesis of mycolic acids, which are essential components of its lipid-rich cell envelope and major contributors to intrinsic drug resistance.

来源:PubMed · Journal of Molecular Biology · pubmed.ncbi.nlm.nih.gov