PubMed · The EMBO Journal· Dan Hu·· 4 天前
感染病学：Tetraspanin CD81 restricts Ebola virus infection and is antagonized by glycoprotein GP and matrix protein VP40.
Tetraspanin CD81 restricts Ebola virus infection and is antagonized by glycoprotein GP and matrix protein VP40.
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原文摘录：Viruses manipulate host cell membranes to evade antiviral immunity, prevent superinfection, and optimize their replication and spread. … Our study provides insights into the roles of NF-κB signaling in Ebola virus replication and immunopathogenesis, and identifies tetraspanin CD81 as a potentially druggable Ebola virus-inhibitory host factor
来源：PubMed · The EMBO Journal · pubmed.ncbi.nlm.nih.gov