诊断与检测:Longitudinal Changes in Exocrine Biomarkers in Children at Risk of Type 1 Diabetes in the ENDIA Study.
原文摘录:OBJECTIVE: The exocrine pancreas is increasingly implicated in type 1 diabetes. Noninvasive biomarkers of exocrine function, fecal elastase-1 (FE-1) and serum immunoreactive trypsin (IRT), may provide early insight into disease pathogenesis.
关注理由:关注诊断与检测时,这项队列研究提供了人群层面的观察线索,随访质量和潜在偏倚值得继续核查。